In short: pixel art's hard, aliased edges are the point — and general-purpose AI background removers are trained to produce smooth, photographic-looking edges, so they blur or feather exactly the edges you need to stay sharp. RemoveGifBG detects flat-color art and preserves hard pixel edges instead of smoothing them.
Pixel art sprites are built pixel-by-pixel on a flat-color background, usually a single solid color chosen specifically so it's easy to key out. That should make background removal the easy case. In practice, running pixel art through a generic background remover often makes it look worse than before: edges that were crisp single-pixel steps come out soft, semi-transparent, or with a faint colored halo — because the tool is trying to produce the kind of soft edge a photograph would have, and pixel art doesn't have that kind of edge to begin with.
RemoveGifBG keeps pixel art edges as hard, binary cuts — a pixel is either kept or removed, with no soft gradient introduced at the boundary. It also skips resizing your art unless you explicitly ask for a size preset, so nothing gets smoothed that you didn't ask to be smoothed.
This applies automatically — the file is analyzed and the flat-color-background case is handled without you needing to pick a specific mode for pixel art versus other content.
Before you upload
See also: Pixel art tool · Game sprite guide